Genetics

Genetic testing, along with your family health history, helps us to better understand your genetic risk towards certain diseases so that we can create a proactive and hands on screening and prevention plan that is tailored just for you.

Artemis provides a variety of genetic tests that help clinicians learn more about an individual’s DNA and the impact their genes can potentially have on their health. 

These tests serve to identify indicators of an increased risk for developing conditions including hereditary cancers, cardiovascular conditions, neurological conditions and certain forms of diabetes. Results from these genetic tests may have an essential impact on screening, medication and treatment recommendations. 

This information also plays a significant role in establishing personalized, long-term health plans, and provides insights into both patients and their biological relatives in regards to medical decisions now and in the future.

Your genes can help you understand whether you are at increased risk for certain health conditions and how your body might process certain medications.

In fact, 10 - 15% of most cancers are due to genetic variants, or changes, that are passed down from your parents. 

Most cases of heart disease are due to lifestyle choices, but some are due to genetics. 

When you take a medication, your response is influenced by many factors, including genetics

Not everyone is a candidate for genetic testing. 

Your personal medical history and your family history can provide the necessary information to determine: 

1) Whether there is a genetic test available for the disease in your family 

2) Whether genetic testing is an option for you to consider.

Artemis Genetic Cardiac Care:

• Heart disease is a leading cause of death worldwide and often runs in families.
• Certain heart conditions are caused by a single harmful DNA variation (or mutation) 
• More than 1 in 200 people have an inherited form of heart disease, but most don’t know it.
• Discuss with your Cardiologist; Geneticist to discuss your family’s heart health. 
• Genetic Testing for the Cardiomyopathies
• To identify a disease-causing mutation in those at-risk family members who have little or no evidence of disease
• Increased clinical surveillance
• Early intervention
• Preventing sequelae of advanced disease
• Treatment interventions - can prevent, delay or treat almost all of the morbid or mortal aspects of the cardiomyopathies
• Genetic testing can help save lives

Artemis Genetic Cancer Care:

• 5 - 10% of all cancers are hereditary (cancers passed down through families via their genes)
• Genetic testing can help you 
• Understand your risk for certain cancers 
• Develop prevention strategies 
• Get the correct screenings 
• Create a more personalized treatment plan if you are diagnosed 
• Help other family members if they are also at risk

Artemis Breast Cancer Care:

• Breast cancer diagnosed at or before age 50 years
• Ovarian cancer
• Multiple primary breast cancers either in one or both breasts
• Male breast cancer
• Triple-negative (estrogen receptor-negative, progesterone receptor-negative, and HER2/neu -negative) breast cancer, particularly < 60 years
• Combination of pancreatic and/or prostate (Gleason score ≥7) with breast, and/or ovarian
• Two or more relatives with breast cancer, one under age 50
• Three or more relatives with breast cancer at any age
• A previously identified BRCA1 or BRCA2 pathogenic variant in the family

Genetic Testing:

• Increased surveillance can identify a cancer at its earliest, most treatable stage
• Certain medicines can prevent cancer from developing (“chemoprevention”)
• If desired, surgery can significantly reduce risk
• Genetic information can qualify you for participation in clinical trials or research studies

• In routine medical practice, Prediabetes is not yet recognized nor treated, although it has been repeatedly demonstrated that the transition to type 2 diabetes can be delayed or avoided  
• Delay of Impaired Glucose Tolerance by a Healthy Lifestyle Trial (DELIGHT) as to the association of 41 SNPs indicating risk for type 2 diabetes with a prediabetic status
• 5 -10% of untreated prediabetic patients will develop diabetes each year 
• 5 - 10% may convert back from the prediabetic status to normoglycemia
• Consult your diabetologist; geneticist to discuss your family’s diabetic health. 
• Genetic markers can be determined early in life, an advantage compared to established risk factors
• Once identified, successful lifestyle intervention trials clearly show that diabetes may be delayed, if not prevented. 
• Get yourself screened

• Severe neurodevelopmental and neuropsychiatric disorder
• Autoimmune neuropsychiatric disorders
• Prenatal maternal-fetal immune interaction affects the fetal brain development
• Both genetic and environmental factors
• Ultimate goal of genetic etiology - discovery of biomarkers for risk assessment, diagnosis, and prediction of therapeutic responses 
• Early intervention in ASD can promote better prognoses, reduce secondary behavioral complications, and even induce normalization of brain activity 
• Known genetic causes are identified in 20-25% of ASD
• There are no single predictable genetic markers for the development of ASD
• Get them screened

Artemis Pharmacogenomic Care:

• It is the process of analysing patients’ genetic codes to see how their bodies will metabolize and respond to certain medications.
• Pharmacogenomics helps doctors make the best decisions regarding the drug dosage
• The right drug, at the right dose, at the right time